Definition of trophoblast - What it is, Meaning and Concept

The notion of trophoblast refers to the set of cells that make up the outer layer of the blastocyst (a state of embryogenesis, that is, , of the growth of the embryo) and which is part of what will later be the placenta .The trophoblast, which begins to form in the early stages of pregnancy, is responsible for providing nutrients to the embryo.

Various kinds of placental cells form the trophoblast, which is responsible for enabling the embryo to implant in the endometrium of the uterus .When it is time to give birth, the woman and her son reject the trophoblast through an immunological process.The trophoblast, however, is usually visible as a kind of membrane that covers the newborn.

It is important to note that a hormone secreted by the trophoblast offers the possibility of warning the state of grav Idez of a woman through blood or urine tests .This hormone, key to the development of pregnancy, is secreted by the outer layer of the trophoblast, which is called syncytiotrophoblast .


This is in direct contact with what is the mother's blood and has the peculiarity that it is responsible for covering the entire surface of the placenta.It performs a very important function since it facilitates the exchange of nutrients between what It is the woman and her baby, as well as gases and waste.


The inner layer of the trophoblast, described as unicellular, is known as citrotrophoblast , although it can also be called Langhans layer .This layer allows the embryonic chorion to attach to the endometrium.


During pregnancy, the doctor may indicate a trophoblast study to analyze the status of the fetus.The trophoblast biopsy , in this sense, involves taking a tissue sample to examine it in a laboratory .This study allows you to discover chromosomal disorders or a disease in genes, for example.


From this aforementioned biopsy it is necessary to know another series of data of interest: • It is performed using a relevant ultrasound • It can be carried out after two months of pregnancy • It can be developed through two different techniques: through the vagina or through an extraction through the abdomen • Sometimes, it is necessary to apply local anesthesia to the pregnant woman so that this action will not be bothered for a few minutes and in which no type of liquid • There are several advantages of using this method and not another.Specifically, it is praised that it can be done in very early stages of pregnancy and that it gives very successful results.• However, it is also true that this biopsy of the trophoblast supposes a higher risk than in amniocentesis that women may suffer a miscarriage.

It should also be stressed that there is what is known as gestational trophoblastic disease that comes to alt To be what is the tissue that will later become the placenta, which can be of various types such as the so-called molar pregnancy.

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