What is MabThera? »Its Definition and Meaning [2019]

MabThera is the commercial name of the active substance rituximab.It is a monoclonal antibody used in the treatment of different types of leukemia and inflammatory diseases such as: lymphomas non-Hodgkin's , chronic lymphocytic leukemia, severe rheumatoid arthritis.Similarly, mabthera is used in combination with steroid medicines in atypical cases of inflammation of the blood vessels and other tissues of the body.

Rituximab it is an antibody, protein type, designed to identify a specific structure, called antigen; found in certain cells of the body and join it

Mabthera (Rituximab) acts by binding to the CD20 antigen of normal and malignant B cells .Then the natural immune defenses of The body attacks and destroys marked B cells. stem cells do not have the CD20 antigen, which makes it possible for B cells to regenerate after the treatment is finished.

Mabthera comes in 2 presentations: box with 2 ampoules with 100mg in 10ml (10mg/ml).Box with 1 vial with 500mg in 50ml (10mg/ml).

It is important to note that the application of mabthera can cause a serious brain infection in the patient , which can lead to the death of the person .Therefore it is recommended to go to the doctor if there is any change in your mental state, or in vision, problems with walking or speaking.They may start slowly and worsen quickly.

If the patient had hepatitis B in the past, it is possible that Mabthera causes this condition to return or get worse.Therefore, your doctor may recommend Performing periodic blood tests to monitor liver function during treatment.

It is advisable not to use mabthera if the patient is allergic to rituximab , if you have had hepatitis B, kidney conditions, if you have a weak immune system, if you have a history of heart conditions.It should not be given to pregnant women, or breastfeeding.

Next, some of the side effects that may manifest in the patient during treatment: chills , fever, cold symptoms, continuous diarrhea, weight loss, pain of ears, headaches, nausea, muscle aches, swelling in m years and feet, sinusitis, continuous cough.